CCS: Connectome Computation System

Submitted by Xi-Nian Zuo on

Connectome Computation System (CCS) extends the functions of FCP scripts onto the cortical surface by integrating FreeSurfer commands and aims to provide a computational platform for multimodal neuroimaging brain connectomics. It contains several unique modules such as quality control procedure (QCP), brain connectome visualization (BCV), test-retest reliability (TRT), multimodal brain parcellation (MBP), and connectome-wide association (CWA). This pipeline has been employed to study the local functional homogeneity (Zuo et al., 2013), the morphological correlates of individual differences in fearful face recognition (Zhao et al., 2013) and Chinese Tai Chi Chuan performance (Wei et al., 2013), the neural correlates of emotion regulation in schizophrenia (Fan et al., 2013), and the default network connectivity in the obsessive-compulsive disorder (Peng et al., 2013).  CCS is developed by the Laboratory for Functional Connectome and Development (LFCD: http://lfcd.psych.ac.cn) in the Institute of Psychology, Chinese Academy of Sciences. The target release of CCS is the end of October, 2013, directly followed by a training course.

References:

[1] Zuo XN*, Xu T, Jiang L, Yang Z, Cao XY, He Y, Zang YF, Castellanos FX, Milham MP. Toward reliable characterization of functional homogeneity in the human brainPreprocessingscan duration,imaging resolution and computational space. Neuroimage. 2013; 65: 374-386.

[2] Peng ZW, Xu T, He QH, Shi CZ, Wei Z, Miao GD, Jing J, Lim KO, Zuo XN*, Chan RCK*. Default network connectivity as a vulnerability marker for obsessive-compulsive disorder. Psychol Med. 2013; In Press.

[3] Zhao K, Chen YX, Yan WJ, Zuo XN, Fu XL*. Amygdala volume predicts inter-individual differences in fearful face recognition. PLoS ONE. 2013; 8(8):e74096.

[4] Wei GX, Xu T, Fan FM, Dong HM, Jiang LL, Li HJ, Yang Z, Luo J*, Zuo XN*. Can Taichi reshape the brain? A brain morphometry study. PLoS ONE. 2013; 8(4): e61038.

[5] Fan FM, Tan SP, Yang FD, Tan YL, Zhao YL, Chen N, Li BB, Song CS, Wang YH, Jin Z, Zhou DF, Milham MP, Zou YZ, Zuo XN. Ventral medial prefrontal functional connectivity and emotion regulation in chronic schizophrenia: A pilot study. Neurosci Bull. 2013; 29(1):59-74.

 

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