Question about the analysis after ROI extraction

Submitted by ygwang on

Dear R-fMRI team,

I have two questions about the statstical analysis for ROI correlation results.

1. ROI Correlation results (e.g. ROICorrelation_Sub001.mat & ROICorrelation_FisherZ_Sub001.mat) would be generated automatically after selecting ROI extraction, and I have 2 groups of subjects, can I directly use the ROI Correlation FisherZ results between the same two ROIs (e.g. ROI1 & ROI2) for each subject in two groups to do the 2 sample t-test?

2. When I did 2 sample t-test for zFC maps for 2 groups, I added "sex", "age" and "head motion" as covariates. But I didn't add these covariates in the 2 sample t-test for ROI correlation FisherZ results. Should I add these covariates too? And if I should, where can I put the covariates in the analysis?

Thanks and look forward to your reply!

Best wishes,

Yuxi