Questions about Repeated Measures ANOVA

Dear Prof Yan

I have some questions about statistical analysis.

In our study, all patients were assigned to three groups, with two different medication treatment and one medication-naive control. And all these patients accepted MRI scan at baseline and after 12 weeks. Now, my question is as followings:

1. Can we compare the group × time interaction effects on brain activity indicators by repeated measures ANOVA, such as ALFF,fALFF and ReHo. At first, I try to do this by mixed-effects comparison, but it can only treat two factors.

2.How can I do the post-hoc analysis by using DPABI?

3. How should I display the final results?





1. DPABI only supports 2x2. You can try SPM.

2. You can do simple effect analysis -> 3. Just extract the ROI values and plot.

感谢严老师的指导!我在使用DPABI 5.0 中的2×2 Mixed Effect 分析后,使用viewer打开生成的interaction F.nii文件时报错,不能打开,而生成的ConditionEffect_T.nii和Group_TwoT.nii 可以正常显示,请问可能是什么原因呢?报错代码如下:

错误使用 repmat
出错 y_AdjustColorMap (line 93)
    NewColorMap(Begin:End,:) = repmat(OriginalColorMap(iColor,:),[Segment 1]);
出错 w_OverlayList>RedrawOverlay (line 1354)
ColorMap = y_AdjustColorMap(ColorMap,...
出错 w_OverlayList>Accept_Callback (line 1423)
            OverlayHeader=RedrawOverlay(OverlayHeader, handles.MainFig);
出错 gui_mainfcn (line 95)
出错 w_OverlayList (line 42)
    gui_mainfcn(gui_State, varargin{:});
出错 @(hObject,eventdata)w_OverlayList('Accept_Callback',hObject,eventdata,guidata(hObject))
错误使用 waitfor
Error while evaluating uicontrol Callback